Publications (2015-Present)
Authors: Bhushan Patwardhan and Rathnam Chaguturu
Year: October 2016
Publisher: Academic Press, Elsevier
ISBN: 9780128018224 / 9780128018149
Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches and advocate the expansion from disease-centric discovery to person-centric therapeutics involving a holistic, multi-target, whole systems approach. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment to expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences.
Authors: Bhushan Patwardhan, Gururaj Mutalik, and Girish Tillu
Year: March 2015
Publisher: Academic Press, Elsevier
ISBN: 012801282X / 978-0128012826
Despite spectacular advances, modern medicine faces formidable global challenges in several key areas- notably the persistence of major killer diseases such as malaria, tuberculosis, leprosy, and newer threats including HIV/AIDS, resistant infections, and Ebola. As such, modern medicine has not led to a significant decrease in chronic diseases like diabetes, obesity, and other degenerative and autoimmune diseases. The authors believe that modern medicine needs to experience a paradigm shift, an integration of traditions- in particular from the ancient systems like Ayurveda and Yoga.
Integrative Approaches for Health: Biomedical Research, Ayurveda and Yoga bring together the basic principles of an interdisciplinary systems approach for an evolving construct of future medicine. Such an approach is already emerging at the cutting edge of current research in omics, bioinformatics, computational and systems biology. Several leading institutions of medicine have adopted Yoga and complementary medicine to widen their reach and deepen their effectiveness in therapeutic practices. The amalgam of modern medicine, with its strengths in scientific rigour, blended with the basic principles of life drawn from Ayurveda and Yoga might evolve into the medicine of tomorrow. Integrative approaches are no longer alternative, perhaps taking these approaches is the only possible way to heal our sick planet. This book introduces important trends and tools for biomedical researchers and physicians alike, to innovate the practice of medicine for the better.
Chopra A, Chavan-Gautam P, Tillu G, Saluja M, Borse S, Sarmukaddam S, et al. Randomized, Double Blind, Placebo Controlled, Clinical Trial to Study Ashwagandha Administration in Participants Vaccinated Against COVID-19 on Safety, Immunogenicity, and Protection With COVID-19 Vaccine-A Study Protocol. Front Med 2022;9:761655.
Saggam A, Kale P, Shengule S, Patil D, Gautam M, Tillu G, et al. Ayurveda-based Botanicals as Therapeutic Adjuvants in Paclitaxel-induced Myelosuppression. Front Pharmacol 2022;13:1–12.
Borse S, Joshi M, Saggam A, Bhat V, Walia S, Marathe A, et al. Ayurveda Botanicals in COVID-19 Management: An in silico Multi-target Approach. PLoS One 2021;16:e0248479.
Saggam A, Limgaokar K, Borse S, Chavan-Gautam P, Dixit S, Tillu G, et al. Withania somnifera (L.) Dunal: Opportunity for Clinical Repurposing in COVID-19 Management. Front Pharmacol 2021;12:623795
Aiyar Y, Chandru V, Chatterjee M, Desai S, Fernandez A, Gupta A, et al. India’s resurgence of COVID-19: urgent actions needed. Lancet (London, England) 2021;397:2232–4.
Patwardhan B, Sarwal R. Significance of AYUSH: India’s first line of defence against COVID-19. J Ayurveda Integr Med 2021;12:227–8.
Chaturvedi S, Tillu G, Kale A, Pendse A, Kulkarni A, Ambike D, et al. Protocol for Infant Massage in Home Settings: An e-Delphi Approach for Consensus Guidance Integrating Traditional Wisdom with Modern Medicine. J Trop Pediatr 2021;67(3):fmab043.
Chopra A, Srikanth N, Patwardhan B. Withania somnifera as a Safer Option to Hydroxychloroquine in the Chemoprophylaxis of COVID-19: Results of Interim Analysis. Complement Ther Med 2021:102768.
Chaturvedi S, Kumar N, Tillu G, Patwardhan B. Research, biomedicine and Ayurveda: From evidence-based medicine to evidence-informed healthcare. Indian J Med Ethics 2021;VI:301–5.
Anand A, Patwardhan B. Whose Duty Is it Anyway? Ann Neurosci 2021;28:5–7.
Patwardhan B, Paranthaman B. Nutrition, food and global health. J Ayurveda Integr Med 2021;12:577–8.
Lele R, Patwardhan B. Transiting from pathy-based to people-centered holistic healthcare. J Ayurveda Integr Med 2020;11:A1--A3.
Patwardhan B, Desiraju G. Assessing research: the slippery slope. Comment Curr Sci 2020;118:25.
Saggam A, Tillu G, Dixit S, Chavan-Gautam P, Borse S, Joshi K, et al. Withania somnifera (L.) Dunal: A Potential Therapeutic Adjuvant in Cancer. J Ethnopharmacol 2020;255:112759.
Patwardhan B, Chavan-Gautam P, Gautam M, Tillu G, Chopra A. Ayurveda Rasayana in Prophylaxis of COVID-19. Curr Sci 2020;19:1158–60.
Tillu G, Chaturvedi S, Chopra A, Patwardhan B. Public Health Approach of Ayurveda and Yoga for COVID-19 Prophylaxis. J Altern Complement Med 2020:acm.2020.0129.
Tillu G, Salvi S, Patwardhan B. AYUSH for COVID-19 management. J Ayurveda Integr Med 2020;11:95–6.
Chaturvedi S, Kumar N, Tillu G, Deshpande S, Patwardhan B. AYUSH, modern medicine and the Covid-19 pandemic. Indian J Med Ethics 2020:1–4.
Mittal P, Radkar A, Kurup A, Kharola A, Patwardhan B. Measuring Access, Quality and Relevance in Higher Education. Econ Polit Wkly 2020;55(24).
Girme A, Saste G, Chinchansure A, Joshi S, Kunkulol R, Hingorani L, et al. Simultaneous Determination of Anthraquinone, Flavonoids, and Phenolic Antidiabetic Compounds from Cassia auriculata Seeds by Validated UHPLC Based MS/MS Method. Mass Spectrom Lett. 2020;11(4):82–9.
Patwardhan B, Chaturvedi S. India in COVID-19 times: Modern and wiser. J Ayurveda and Integr Med 2020; 11: 367–368.
Chaturvedi S, Randive B, Pathak A, Agarkhedkar S, Tillu G, Darmstadt GL, et al. Prevalence and perceptions of infant massage in India: study from Maharashtra and Madhya Pradesh states. BMC Pediatr. 2020;20(1):512.
Patwardhan B, Patwardhan K. Contesting Predators: Cleaning Up Trash in Science. J Altern Complement Med 2019;25:979–82.
Patwardhan B, Thakur A. UGC-CARE initiative to promote research quality, integrity and publication ethics. Comment Curr Sci 2019;117.
Shengule S, Mishra S, Patil D, Joshi K, Patwardhan B. Phytochemical characterization of ayurvedic formulations of Terminalia arjuna: A potential tool for quality assurance. Indian J Tradit Knowl 2019;18:127–32.
Grudniewicz A, Moher D, Cobey K, Bryson GL, Cukier S, Allen K, et al. Predatory journals: no definition, no defence. Nature 2019;576:210–2.
Girme A, Saste G, Ghule C, Gaikar N, Kunkulol R, Patwardhan B, et al. Phytoanalytical profiling of Cassia auriculata by LC-PDA-ESI-MS / MS and HPTLC supporting its metabolic claims. 67th Int Congr Annu Meet Soc Med Plant Nat Prod Res Coop with French Soc Pharmacogn AFERP 2019;85.
Tillu G. AYUSH and meta-research. J Ayurveda Integr Med 2019;10:157–8.
Mutalik G, Tillu G, Patwardhan B. AyurYoga, the confluence of healing sciences: A call for global action. J Ayurveda Integr Med 2019;10:79–80.
Patwardhan B. Why India is striking back against predatory journals. Nature. 2019 Jul;571(7763):7.
Patwardhan B, Payyappalli U. Ayurveda and anti-microbial resistance. J Ayurveda Integr Med 2018;9:85–6.
Patwardhan B, Nagarkar S, Gadre S, Lakhotia S, Katoch V, Moher D. A critical analysis of the “UGC-approved list of journals.” Curr Sci 2018;114:1299–303.
Tillu G. AYUSH research for New India: Vision and strategies. J Ayurveda Integr Med 2018;9:240–4.
Patwardhan B, Tillu G. A tribute to the visionaries. J Ayurveda Integr Med 2018;9:159–60.
Patwardhan B, Tillu G. Universal Health Coverage and AYUSH systems. J Ayurveda Integr Med 2018;9:1–2.
Shengule S, Kumbhare K, Patil D, Mishra S, Apte K, Patwardhan B. Herb-drug interaction of Nisha Amalaki and Curcuminoids with metformin in normal and diabetic condition: A disease system approach. Biomed Pharmacother 2018;101:591–8.
Shankar D, Patwardhan B. AYUSH for New India: Vision and strategy. J Ayurveda Integr Med 2017;8:137–9.
Patwardhan K, Patwardhan B. Ayurveda education reforms in India. J Ayurveda Integr Med 2017;8:59–61.
Mukherjee P, Katiyar C, Patwardhan B. Editorial: Special issue on Ayurveda. J Ethnopharmacol 2017;197:2.
Chandran U, Patwardhan B. Network ethnopharmacological evaluation of the immunomodulatory activity of Withania somnifera. J Ethnopharmacol 2016;197:250–6.
Chaturvedi S, Raven J, Patwardhan B. Addressing child under nutrition: can traditional practices offer a solution? Glob Health Action 2017;10:1327255.
Patwardhan B. Indian Science and Predatory Journals. J Ayurveda Integr Med 2017;8:1–2.
Patwardhan B, Tillu G. J-AIM: Progress, policy and future plans. J Ayurveda Integr Med 2017;8:213–4.
Sanap A, Chandravanshi B, Shah T, Tillu G, Dhanushkodi A, Bhonde R, et al. Herbal pre-conditioning induces proliferation and delays senescence in Wharton’s Jelly Mesenchymal Stem Cells. Biomed Pharmacother 2017;93:772–8.
Patwardhan K, Tillu G, Jadhav P. Good practices of publishing AYUSH research: A practical checklist for authors. J Ayurveda Integr Med 2017;8:132–6.
Patwardhan B. Integrity of Ayurveda. J Ayurveda Integr Med 2016;7:189–90.
Chaturvedi S, Patwardhan B. Building bridges for integrative medicine. The Lancet Psychiatry 2016;3:705–6.
Patwardhan B. Ayurvedic drugs in case: Claims, evidence, regulations and ethics. J Ayurveda Integr Med 2016;7:135–7.
Patwardhan B. Ayurvedic drugs in case: Claims, evidence, regulations and ethics. J Ayurveda Integr Med 2016;7:135–7.
Patwardhan B. Strengthening the Ayurveda ecosystem. J Ayurveda Integr Med 2016;7:73–5.
Patwardhan B. Strategic cooperation with WHO. J Ayurveda Integr Med 2016;7:1–2.
Patwardhan B. Need to Recognize Efforts From Developing Countries. J Bioeth Inq 2016;13:19.
Roy A, Patwardhan B, Chaguturu R. Reigniting pharmaceutical innovation through holistic drug targeting. Drug Discov World 2016;17:45–55.
Patwardhan B, Chaguturu R. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting. 2016.
Ghodke-Puranik Y, Puranik A, Shintre P, Joshi K, Patwardhan B, Lamba J, et al. Folate metabolic pathway single nucleotide polymorphisms: a predictive pharmacogenetic marker of methotrexate response in Indian (Asian) patients with rheumatoid arthritis. Pharmacogenomics. 2015;16:2019–34.
Rotti H, Mallya S, Kabekkodu S, Chakrabarty S, Bhale S, Bharadwaj R, et al. DNA methylation analysis of phenotype specific stratified Indian population. J Transl Med. 2015;13:151.
Nizamuddin S, Govindaraj P, Saxena S, Kashyap M, Mishra A, Singh S, et al. A novel gene THSD7A is associated with obesity. Int J Obes. 2015;39:1662–5.
Govindaraj P, Nizamuddin S, Sharath A, Jyothi V, Rotti H, Raval R, et al. Genome-wide analysis correlates Ayurveda Prakriti. Sci Rep. 2015;5:15786.
Patwardhan B. Ready for the next leap. J Ayurveda Integr Med. 2015;6:223–4.
Patwardhan B. Public perception of AYUSH. J Ayurveda Integr Med 2015;6:147–9.
Patwardhan B. Good publications need good research. J Ayurveda Integr Med 2015;6:73–4.
Patwardhan B, Mashelkar R. Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Drug Discov Today 2009;14:804–11.
Patwardhan B, Chandran U. Network Ethnopharmacology Approaches for Formulation discovery. Ind J Trad Know 2015;14(4):574-580
Patwardhan B. National health policy: Need to innovate. J Ayurveda Integr Med 2015;6:1–3.
Raut A, Tillu G, Vaidya A. Reverse pharmacology effectuated by studies of Ayurvedic products for arthritis. Curr Sci 2016;111:337–42
Patwardhan B, Deshpande S, Tillu G, Mutalik G. In Search of Roots: Tracing the History and Philosophy of Indian Medicine. Indian J Hist Sci 2015;50:629–41.
Chandran U, Mehendale N, Tillu G, Patwardhan B. Network Pharmacology of Ayurveda Formulation Triphala with Special Reference to Anti-Cancer Property. Comb Chem High Throughput Screen 2015;18:846–54.
Chandran U, Mehendale N, Tillu G, Patwardhan B. Network pharmacology: an emerging technique for natural product drug discovery and scientific research on ayurveda. Proc Indian Natl Sci Acad 2015;81(3):8.
Tillu G, Chopra A, Sarmukaddam S, Tharyan P. Ayurveda interventions for rheumatoid arthritis. Cochrane Database Syst Rev 2015;2015.
Patwardhan B, Mutalik G, Tillu G. Integrative Approaches for Health: Biomedical Research, Ayurveda and Yoga. 1st ed. Amsterdam: Elsevier Inc.; 2015.
Patwardhan B, Tillu G, Sardeshpande N, Deshpande S, Gadhve S. Human Resource Development in Health Services. Econ Polit Wkly 2015;50(36).
Patwardhan B. Chapter 12 - Traditional Medicine-Inspired Evidence-Based Approaches to Drug Discovery. In: Mukherjee PK, editor. Evidence-Based Validation of Herbal Medicine. Boston: Elsevier; 2015. p. 259–72.
Rotti H, Raval R, Anchan S, Bellampalli R, Bhale S, Bharadwaj R, et.al. Determinants of prakriti, the human constitution types of Indian traditional medicine and its correlation with contemporary science. J Ayurveda Integr Med. 2014 Jul;5(3):167-75.
Patil D, Gautam M, Gairola S, Jadhav S, Patwardhan B. HPLC/Tandem Mass Spectrometric Studies on Steroidal Saponins: An Example of Quantitative Determination of Shatavarin IV from Dietary Supplements Containing Asparagus racemosus, Journal of AOAC INTERNATIONAL, Volume 97, Issue 6, 1 November 2014, Pages 1497–1502.
Patwardhan B. The new pharmacognosy. Comb Chem High Throughput Screen. 2014 Feb;17(2):97.
Patwardhan B, Mutalik G. Search of novel model for integrative medicine. Chin J Integr Med. 2014 Mar;20(3):170-8.
Gadgil M, Joshi K, Pandit A, Otiv S, Joshi R, Brenna J, et.al. Imbalance of folic acid and vitamin B12 is associated with birth outcome: an Indian pregnant women study. Eur J Clin Nutr. 2014 Jun;68(6):726-9.
Gadgil M, Joshi K, Naik S, Pandit A, Otiv S, Patwardhan B. Association of homocysteine with global DNA methylation in vegetarian Indian pregnant women and neonatal birth anthropometrics. J Matern Fetal Neonatal Med. 2014 Nov;27(17):1749-53.
Patil D, Gautam M, Gairola S, Jadhav S, Patwardhan B. Effect of botanical immunomodulators on human CYP3A4 inhibition: implications for concurrent use as adjuvants in cancer therapy. Integr Cancer Ther. 2014 Mar;13(2):167-75.
Patwardhan B. Bridging Ayurveda with evidence-based scientific approaches in medicine. EPMA J. 2014 Nov 1;5(1):19.
Patwardhan B. Traditions, rituals and science of Ayurveda. J Ayurveda Integr Med. 2014 Jul;5(3):131-3.
Raut A, Bichile L, Chopra A, Patwardhan B, Vaidya A. Comparative study of amrutbhallataka and glucosamine sulphate in osteoarthritis: Six months open label randomized controlled clinical trial. J Ayurveda Integr Med. 2013 Oct;4(4):229-36.
Chopra A, Saluja M, Tillu G, Sarmukkaddam S, Venugopalan A, Narsimulu G, et.al. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial. Rheumatology (Oxford). 2013 Aug;52(8):1408-17.
Patwardhan B. Traditional knowledge patents: New guidelines or deterrents? J Ayurveda Integr Med. 2013 Jan;4(1):1-3.
Patwardhan B. Ethical and scientific aspects of research publications. J Ayurveda Integr Med. 2013 Jul;4(3):129-31.
Patil D, Gautam M, Mishra S, Karupothula S, Gairola S, Jadhav S. et.al. Determination of withaferin A and withanolide A in mice plasma using high-performance liquid chromatography-tandem mass spectrometry: application to pharmacokinetics after oral administration of Withania somnifera aqueous extract. J Pharm Biomed Anal. 2013 Jun;80:203-12.
Patwardhan B. Historical future of Ayurveda. J Ayurveda Integr Med. 2013 Oct;4(4):189-92.
Patwardhan B. Historical future of Ayurveda. J Ayurveda Integr Med. 2013 Oct;4(4):189-92.
Patwardhan B. Time for evidence-based Ayurveda: A clarion call for action. J Ayurveda Integr Med. 2013 Apr;4(2):63-6.
Chopra A, Saluja M, Tillu G, Venugopalan A, Narsimulu G, Sarmukaddam S, et.al. Evaluating higher doses of Shunthi - Guduchi formulations for safety in treatment of osteoarthritis knees: A Government of India NMITLI arthritis project. J Ayurveda Integr Med. 2012 Jan;3(1):38-44.
Patwardhan B. Adding life to years with Ayurveda. J Ayurveda Integr Med. 2012 Apr;3(2):55-6.
Patwardhan B. Health for India: Search for appropriate models. J Ayurveda Integr Med. 2012 Oct;3(4):173-4.
Chopra A, Saluja M, Tillu G, Venugopalan A, Sarmukaddam S, Raut A, et.al. A Randomized Controlled Exploratory Evaluation of Standardized Ayurvedic Formulations in Symptomatic Osteoarthritis Knees: A Government of India NMITLI Project. Evid Based Complement Alternat Med. 2011;2011:724291.
Sumantran V, Joshi A, Boddul S, Koppikar S, Warude D, Patwardhan B, et.al. Antiarthritic activity of a standardized, multiherbal, Ayurvedic formulation containing Boswellia serrata: in vitro studies on knee cartilage from osteoarthritis patients. Phytother Res. 2011 Sep;25(9):1375-80.
Chopra A, Saluja M, Tillu G, Venugopalan A, Narsimulu G, Handa R, et.al. Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA): a randomized investigator-blind controlled study. Clin Rheumatol. 2012 Feb;31(2):259-69.
Patwardhan B. Ayurveda GCP Guidelines: Need for freedom from RCT ascendancy in favor of whole system approach. J Ayurveda Integr Med. 2011 Jan;2(1):1-4.
Patwardhan B, Joglekar V, Pathak N, Vaidya A. (2011). Vaidya-Scientists: Catalysing Ayurveda Renaissance. Current science. 100. 476-486.
Ghodke Y, Chopra A, Shintre P, Puranik A, Joshi K, Patwardhan B. Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians. Indian J Med Res. 2011 Mar;133(3):274-9
Puranik A, Halade G, Kumar S, Mogre R, Apte K, Vaidya A, Patwardhan B. Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction. Evid Based Complement Alternat Med. 2011;2011:915240.
Ghodke Y, Joshi K, Patwardhan B. Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability. Evid Based Complement Alternat Med. 2011;2011:249528.
Patil D, Gautam M, Jadhav U, Mishra S, Karupothula S, Gairola S. Physicochemical Stability and Biological Activity of Withania somnifera Extract under Real-Time and Accelerated Storage Conditions. Planta Medica, Jan 1, 2010
Patwardhan B, Vaidya A. Natural products drug discovery: accelerating the clinical candidate development using reverse pharmacology approaches. Indian J Exp Biol. 2010 Mar;48(3):220-7.
Patil, D., Gautam, M., Mishra, S. et al. Quantitative Determination of Protoberberine Alkaloids in Tinospora cordifolia by RP-LC-DAD. Chroma 71, 341–345 (2010).
Patwardhan B. Ayurveda for all: 11 action points for 2011. J Ayurveda Integr Med. 2010 Oct;1(4):237-9.
Patwardhan B. Ayurveda, evidence-base and scientific rigor. J Ayurveda Integr Med. 2010 Jul;1(3):169-70.
Patwardhan B. J-AIM receives warm welcome. J Ayurveda Integr Med. 2010 Apr;1(2):85-6.
Patwardhan B. Ayurveda and integrative medicine: Riding a tiger. J Ayurveda Integr Med. 2010 Jan;1(1):13-5.
Patwardhan B. J-AIM - A Renaissance for Ayurveda. J Ayurveda Integr Med. 2010 Jan;1(1):1-2.
Patwardhan B, Chopra A, Narsimulu G, Handa R, Bichile L, Qazi GN, et al. A synergistic herbal composition for treatment of rheumatic and musculo-skeletal disorders (rmsds) [Internet]. World Intellectual Property Organization International Bureau; WO 2009/010992 A2, 2009 [cited 2021 Sep 18]. p. 47.
Gautam M, Patwardhan B. Aqueous extracts of plant products. India; 234927, 2009.
Jadhav SS, Patwardhan B, Gautam M. Adjuvant composition for vaccine. United States of America; US8501186B2, 2013. p. 22.
Patwardhan B, Vaidya ADB. Ayurveda: scientific research and publications. Curr Sci. 2009;97(8):1117–21.
Patwardhan B, Mashelkar R. Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Drug Discov Today. 2009;14(15–16):804–11.
Kurup A, Mohan A, Patwardhan B. (2009). Emerging directions in global education. Current Science. 96. 1301-1303.
Sahoo N, Sarkar S, Patwardhan B. Stability Study on Boswellia serrata (Hydro-alcoholic) Extract. Asian J Chem. 2009;21(5):3529–34.
Gautam M, Saha S, Bani S, Kaul A, Mishra S, Patil D, et.al. Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immunoadjuvant potential. J Ethnopharmacol. 2009 Jan 21;121(2):241-7.
Chitlange S, Kulkarni P, Patil D, Patwardhan B, Nanda R. High-performance liquid chromatographic fingerprint for quality control of Terminalia arjuna containing Ayurvedic churna formulation. J AOAC Int. 2009 Jul-Aug;92(4):1016-20.
Patwardhan B, Vaidya A, Chorghade M, Joshi S. Reverse Pharmacology and Systems Approaches for Drug Discovery and Development, Current Bioactive Compounds 2008; 4(4) .
Sumantran V, Chandwaskar R, Joshi A, Boddul S, Patwardhan B, Chopra A.et.al. The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro. Phytother Res. 2008 Oct;22(10):1342-8.
Gautam M, Gairola S, Jadhav S, Patwardhan B. Ethnopharmacology in vaccine adjuvant discovery. Vaccine. 2008 Sep 26;26(41):5239-40.
Sumantran VN, Kulkarni A, Chandwaskar R, Harsulkar A, Patwardhan B, Chopra A, et.al. Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis. Evid Based Complement Alternat Med. 2008 Sep;5(3):329-35.
Chavan P, Warude D, Joshi K, Patwardhan B. Development of SCAR (sequence-characterized amplified region) markers as a complementary tool for identification of ginger (Zingiber officinale Roscoe) from crude drugs and multicomponent formulations. Biotechnol Appl Biochem. 2008 May;50(Pt 1):61-9.
Keramat A, Patwardhan B, Larijani B, Chopra A, Mithal A, Chakravarty D, Adibi H, Khosravi A. The assessment of osteoporosis risk factors in Iranian women compared with Indian women. BMC Musculoskelet Disord. 2008 Feb 27;9:28.
Ghodke Y, Joshi K, Arya Y, Radkar A, Chiplunkar A, Shintre P, et al. Genetic polymorphism of CYP2C19 in the Maharashtrian population. Eur J Epidemiol. 2007;22:907–15.
Shinde V, Dhalwal K, Mahadik K, Joshi K, Patwardhan B. RAPD Analysis for Determination of Components in Herbal Medicine. Evid Based Complement Alternat Med. 2007 Sep;4(Suppl 1):21-3.
Joshi K, Hankey A, Patwardhan B. Traditional phytochemistry: identification of drug by 'taste'. Evid Based Complement Alternat Med. 2007 Jun;4(2):145-8.
Sumantran VN, Kulkarni A, Boddul S, Chinchwade T, Koppikar SJ, Harsulkar A, et.al. Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis. J Biosci. 2007 Mar;32(2):299-307.
Patwardhan B, Gautam M. Ethnopharmacology Approaches for Botanical Immunomodulators and Chemoprotectants in Cancer Therapy. In: Leung P-C, Fong H, editors. Annals.
Chavan P, Joshi K, Patwardhan B. DNA microarrays in herbal drug research. Evid Based Complement Alternat Med. 2006 Dec;3(4):447-57.
Hankey A, Patwardhan B. Second World Ayurveda Congress: University of Pune, Pune, Maharashtra, India, November 5–12, 2006. Evid Based Complement Altern Med. 2006;3(4):547–8.
Warude D, Chavan P, Joshi K, Patwardhan B. Development and Application of RAPD-SCAR Marker for Identification of Phyllanthus emblica LINN., Biological and Pharmaceutical Bulletin, 2006, Volume 29, Issue 11, Pages 2313-2316, Released on J-STAGE November 01, 2006
Bani S, Gautam M, Sheikh F, Khan B, Satti N, Suri K, et al. Selective Th1 up-regulating activity of Withania somnifera aqueous extract in an experimental system using flow cytometry. J Ethnopharmacol. 2006;107(1):107–15.
Patwardhan B, Gautam M, Diwanay S. Botanical Immunomodulators and Chemoprotectants in Cancer Therapy. In: Chorghade M, editor. Drug Discovery and Development: Drug Discovery, Volume 1. John Wiley & Sons, Inc.; 2006. p. 405–24.
Joshi K, Lad S, Kale M, Patwardhan B, Mahadik SP, Patni B, et.al. Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD). Prostaglandins Leukot Essent Fatty Acids. 2006 Jan;74(1):17-21.
Patwardhan B. Traditional Medicine for Global Health: Public Health and Intellectual Property Aspects. Asia pacific Technical Monitor, UN APCTT, New Delhi, India. 2006.
Patwardhan B, Warude D, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: a comparative overview. Evid Based Complement Alternat Med. 2005 Dec;2(4):465-73.
Patwardhan B. Ethnopharmacology and drug discovery. J Ethnopharmacol. 2005 Aug 22;100(1-2):50-2.
Ghodke Y, Joshi K, Chopra A, Patwardhan B. HLA and disease. Eur J Epidemiol. 2005;20(6):475-88.
Patwardhan B, Joshi K, Chopra A. Classification of human population based on HLA gene polymorphism and the concept of Prakriti in Ayurveda. J Altern Complement Med. 2005 Apr;11(2):349-53.
Patwardhan B, Gautam M. Botanical immunodrugs: scope and opportunities. Drug Discov Today. 2005 Apr 1;10(7):495-502.
Diwanay S, Gautam M, Patwardhan B. Cytoprotection and immunomodulation in cancer therapy. Curr Med Chem Anticancer Agents. 2004 Nov;4(6):479-90.
Chopra A, Lavin P, Patwardhan B, Chitre D. A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees. J Clin Rheumatol. 2004 Oct;10(5):236-45.
Gautam M, Diwanay S., Gairola S, Shinde Y., Jadhav S., Patwardhan B. Immune response modulation to DPT vaccine by aqueous extract of Withania somnifera in experimental system. Int Immunopharmacol. 2004;4(6):841–9.
Gautam M, Diwanay S, Gairola S, Shinde Y, Patki P, Patwardhan B. Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental system. J Ethnopharmacol. 2004;91(2–3):251–5.
Patwardhan B, Vaidya ADB, Chorghade M. Ayurveda and natural products drug discovery. Curr Sci. 2004;86(6):789–99.
Diwanay S, Chitre D, Patwardhan B. Immunoprotection by botanical drugs in cancer chemotherapy. J Ethnopharmacol. 2004;90(1):49–55.
Patwardhan B, Chopra A, Vaidya ADB. Herbal remedies and the bias against ayurveda. Curr Sci . 2003;84(9):1165-6.
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Vaidya RA, Vaidya AD, Patwardhan B, Tillu G, Rao Y. Ayurvedic pharmacoepidemiology: a proposed new discipline. J Assoc Physicians India. 2003 May;51:528.
Warude D, Chavan P, Joshi K, Patwardhan B. DNA isolation from fresh, dry plant samples with highly acidic tissue extracts. Plant Mol Biol Rep. 2003;21:467.
Patwardhan BK. Ayurveda: The “Designer” medicine. Indian Drugs. 2000;37(5):213–27.
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Chopra A, Lavin P, Patwardhan B, Chitre D. Randomized double blind trial of an ayurvedic plant derived formulation for treatment of rheumatoid arthritis. J Rheumatol. 2000 Jun;27(6):1365-72.
Agarwal R, Diwanay S, Patki P, Patwardhan B. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. J Ethnopharmacol. 1999;67(1):27–35.
Patil, M. S. et al. Antistress Activity of Tinospora cordifolia (Wild) Miers. Indian drugs 34 (1997): 211-215.
Patwardhan B. Method of treating musculoskeletal disease and a novel composition therefor. United States; 5494668, 1996.
Ziauddin M, Phansalkar N, Patki P, Diwanay S, Patwardhan B. Studies on the immunomodulatory effects of Ashwagandha. J Ethnopharmacol. 1996 Feb;50(2):69-76.
Grandhi A, Mujumdar AM, Patwardhan B. A comparative pharmacological investigation of Ashwagandha and Ginseng. J Ethnopharmacol. 1994 Dec;44(3):131-5.
Kulkarni R, Patki P, Jog V, Gandage S, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991;33(1–2):91–5.
Patwardhan B, Walimbe VV, Palkar V, Kulkarni PH. Studies on ayurvedic tablets - part I disintegration time as a preliminary tool for standardisation. Anc Sci Life. 1990 Jul;10(1):36-9.
Patwardhan B, Bhutani K, Patki P, Dange S, Gore D, Borole D, et.al. Clinical Evaluation of Terminalia belerica in Diarrhoea. Anc Sci Life; 1990;10(2):94-97
Patki PS, Singh J, Gokhale SV, Bulakh PM, Shrotri DS, Patwardhan B. Efficacy of potassium and magnesium in essential hypertension: a double-blind, placebo controlled, crossover study. BMJ. 1990 Sep 15;301(6751):521-3.
Paranjpe P, Patki P, Patwardhan B. Ayurvedic treatment of obesity: a randomised double-blind, placebo-controlled clinical trial. J Ethnopharmacol. 1990 Apr;29(1):1-11.
Patki PS, Gokhale GS, Singh J, Shrotri DS, Patwardhan B. Potassium and magnesium in essential hypertension. Br Med J. 1990;301(6763):1279.
Saraf M, Ghooi R, Patwardhan B. Studies on the mechanism of action of Semecarpus anacardium in rheumatoid arthritis. J Ethnopharmacol. 1989;25(2):159–164.
Patwardhan B, Ghooi R, David S. A new anaerobic inhibitor of herbal origin. Indian J Pharm Sci. 1988;50(2):130–2.
Patwardhan B, Francis R, Kapre S, Sharma K. Antibacterial activity of Semecarpus anacardium extracts. Bull Haffkine Inst. 1982;10(2):27-30
Lamture J, Gondgaon N, Nayak U, Patwardhan B, Ghooi R. Semecarpus anacardium. Separation of the bhilawanols A and B and a comparative study of their growth inhibitory effect on Clostridium tetani and general pharmacology. Bull Haffkine Inst. 1982;10(3):87-92
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